Program
The master’s program will provide students with a broad knowledge in the field of neuroscience ranging from molecular and cellular to integrative neuroscience.
• High-skilled researchers, clinicians and experts in the vast and ever-growing field of neuroscience coming from universities, research institutes, hospitals, and industries
• Experimental skills using cutting-edge techniques (ten-month internship in Paris or abroad)
• Skills in project management, experimental design, data analysis, and scientific communication.
• Over 50 research laboratories and facilities involved in this program
A master’s degree for motivated students willing to pursue a career in the field of neuroscience, in both public and private sectors. An access to different PhD schools in France and abroad.
During the first year (M1), students will acquire a solid theoretical knowledge in neuroscience with an emphasis on experimental neuroscience research.
- Courses taught in English or in French
- State-of-the-art technology in neuroscience research
- Methodology in neuroscience taught during each semester
- An overall four-month internship is required to validate the M1 level, either a long internship abroad, or 2 different internships 2 months each
Our facilities of cutting-edge technologies are actively involved during internships and lab sessions
CORE MODULES
- Functional neuroanatomy
- Development and evolution of the nervous system
- Sensorimotor and cognitive systems
- Neuropharmacology
- Neurophysiology
- Neuroscience of homeostatic processes
- Cellular mechanisms of neuropathologies
- Scientific communication
- Neural data science with Python
- Lab sessions
CORE MODULES
- Models, experimental design and statistics
- Project management and scientific valorization
INTERNSHIP
- Two internships in different locations (research lab, facility of cutting-edge technology, or industry OR one long internship abroad (4 months)
During the second year (M2), students will acquire more in-depth knowledge in different fields of neuroscience.
Core and optional modules in cellular and molecular neuroscience and integrative neuroscience are offered.
Students can take one free module from other master’s degrees (Master of genetics, CogMaster, BME,..).
- Courses taught in English
- State-of-the-art technology in neuroscience research
- Personal and team working to elaborate a research project in neuroscience
- An overall six-month internship in France or abroad is required to validate the M2 level
CORE MODULES
- Neuroimaging
- Nervous system disorders and repair
- Drug discovery for nervous system
- Research proposal
OPTIONAL MODULES IN CELLULAR AND MOLECULAR NEUROSCIENCE
- Brain plasticity
- Glial and non-neuronal cell biology
- RNA regulation in the CNS
- Neuro-epigenetics
OPTIONAL MODULES IN INTEGRATIVE NEUROSCIENCE
- Systems neuroscience
- Neurogenetics, psychiatry and behaviour
- Brain and metabolism (Master NuMéSi)
- Cognitive neuroscience (CogMaster)
+ ONE FREE MODULE IN OTHER MASTERS OR FROM OPTIONAL MODULES
SIX-MONTH INTERNSHIP
in an academic research lab in France or abroad
Program
The Neuroscience master’s program will provide students with a broad knowledge in the field of neuroscience ranging from molecular and cellular to integrative neuroscience.
- High-skilled researchers, clinicians and experts in the vast and ever-growing field of neuroscience coming from universities, research institutes, hospitals, and industries
- Experimental skills using cutting-edge techniques (ten-month internship in Paris or abroad)
- Skills in project management, experimental design, data analysis, and scientific communication.
- Over 50 research laboratories and facilities involved in this program
A master’s degree for motivated students willing to pursue a career in the field of neuroscience, in both public and private sectors. An access to different PhD schools in France and abroad.
During the first year of the program (M1), students will acquire a solid theorical knowledge in neuroscience with an emphasis on experimental neuroscience research.
→ Courses taught in English and in French (depending on the teaching unit)
→ State-of-the-art technology in neuroscience research
→ Methodology in neuroscience taught during each semester
→ An overall four-month internship is required to validate the first year, either a long internship abroad or two different two-month internships
Our facilities of cutting-edge technologies are actively involved during internships and lab sessions.
SEMESTER 1
SEMESTER 2
CORE MODULES
– Models, experimental design and statistics
– Project management and scientific valorization
INTERNSHIP
– Two two-month internships in different locations (research lab, facility of cutting-edge technology, or industry OR one long internship abroad (4 months) – full description –
During the second year of the program (M2), students will acquire more in-depth knowledge in different fields of neuroscience. Core and optional modules in cellular and molecular neuroscience and integrative neuroscience are offered. Students can take one free module from other master’s degrees (Master of Genetics, BioMedical Engineering, CogMaster, …)
→ Courses taught in English
→ State-of-the-art technology in neuroscience research
→ Personal and team working to elaborate a research project in neuroscience
→ An overall six-month internship in France or abroad is required to validate the M2 level
SEMESTER 3
CORE MODULES
– Glial and non-neuronal cell biology
– Nervous system disorders and repair
– Drug discovery for nervous system
OPTIONAL MODULES IN CELLULAR AND MOLECULAR NEUROSCIENCE
OPTIONAL MODULES IN INTEGRATIVE NEUROSCIENCE
– Neurogenetics, psychiatry and behaviour
+ ONE FREE MODULE IN OTHER MASTERS OR FROM OPTIONAL MODULES
SEMESTER 4
INTERNSHIP
– Six-month internship in an academic research lab in France or abroad – full description –
Course Title: Neuronal Networks
Course supervisor:
- Aude MARZO (MCU Université de Paris),
Description: “Neuronal Networks” aims at deepening your knowledge on neuronal networks. You will explore differential integration of synaptic inputs, and signal modulation with various example of synaptic plasticity. You will also be introduced to computational neurosciences with the presentation of classical models for single neuron firing and communication in neural networks.
Key words: synaptic plasticity; dendritic integration; computational neurosciences; learning and memory
Total number of hours: 24 Number of ECTS: 3 Semester 3
Optional course ☒
Prerequisites/skills needed: Master 1 in Neuroscience ; good understanding of cellular electrophysiology
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Scientific communication
Course supervisor:
- Cendra AGULHON (CR CNRS),
- Mehrnaz JAFARIAN-TEHRANI (Prof. Université de Paris)
Description: The main objective is to learn how to communicate scientific information: writing skills for mini-reviews, articles, posters and oral presentations, and creation of audio slideshows. Workgroup of students will (i) follow seminars delivered in English by our guest renowned neuroscientists, (ii) interview them, and (iii) organize mini-symposiums to present scientific articles (via talks and posters) as well as present scientific concepts and discoveries to general public.
Key words: Scientific communication via oral and poster presentations, interviews of guest researchers, audio slideshows, popular scientific communications, mini-review and article writing
Total number of hours: 24 Number of ECTS: 3 Semester 1
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: Scientific background in biology
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Neuroimaging
Course supervisor:
- Clément RICARD (MCU Université de Paris)
Description: Give an overview of the different neuroimaging techniques and approaches from the researcher, clinician and industrial point of view.
Key words: Neuroimaging, Optics, MRI, CT-Scan, Ultrasound, Nuclear imaging
Total number of hours: 24 Number of ECTS: 3 Semester 3
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: Knowledge in neuroanatomy (attending the M1 « Neuroanatomie fonctionnelle » course is not mandatory but recommended).
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Drug Discovery for Nervous system
Course supervisor:
- Nicolas MARIE (CR CNRS)
- Charbel MASSAAD (Prof. Université de Paris)
Description: Neuropharmacology is the study and understanding of the actions of chemical agents on neurobiological processes in nervous system. Students will discover the recent advances in neuropharmacology and some aspects of the development of drugs for the nervous system regarding medical specialties.
Key words: Optopharmacology, drug development, biased ligands, drug delivery
Total number of hours: 24 Number of ECTS: 3 Semester 3
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: Strong background in physiology and neuropharmacology
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Epigenetic, development and brain integrity
Course supervisor:
- Valérie MEZGER (DR CNRS)
- Délara SABERAN-DJONEIDI (MCU Université de Paris)
- Véronique DUBREUIL (MCU Université de Paris)
Description: The course aims at providing in-depth research-based knowledge about the epigenetic processes that govern behaviors and brain functions. The student will appreciate how basic epigenetic mechanisms tightly regulate brain development, neural cell differentiation and brain integrity, and how the perturbation of normal epigenetic processes lead to a wide spectrum of neurodevelopmental and neuropsychiatric disorders. Moreover, special focus will be put on the impact of environmental insults on the neural epigenome and neural cell fate during development and in a lifetime manner, to the protective responses, which underlies the proper brain functions.
Key words: Epigenome, neurodevelopment, brain integrity, NGS, cohort analysis, neurodegenerescence
Total number of hours: 24 Number of ECTS: 3 Semester 3
Optional course ☒ (maximum 16 students)
Prerequisites/skills needed: brain development, molecular and cellular biology
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Glial and non-neuronal cell biology
Course supervisor:
- Charbel MASSAAD (Prof. Université de Paris)
- Mehrnaz JAFARIAN-TEHRANI (Prof. Université de Paris)
Description: The aim of this teaching unit is to learn the recent advances in glial biology and glial and non-glial cell interactions. Besides the main courses, tutorials will guide the students to perform innovative academic project based on the topics developed during the main lectures.
Key words: schwann cell, astrocyte, oligodendrocyte, microglia, endothelial cell, neurovascular unit, cell interaction, neuron-glia interaction
Total number of hours: 24 Number of ECTS: 3 Semester 3
Mandatory course ☒
Prerequisites/skills needed: cellular and molecular neurobiology, electrophysiology
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Systems and integrative Neuroscience
Course supervisor:
- Mathieu BERANECK (CR CNRS)
Description: the goal of the Systems and Integrative Neuroscience course is to provide the student the basic knowledge regarding the methodologies and approaches used to study functional neural systems. The course brings together teachers and researchers who are studying different functions on various species. They all work to understand how functions emerge by studying their respective systems at different levels with a so-called integrative approach. For each system we will consider the role of the electrophysiological properties of the neurons, of the properties that emerge from neural networks and microcircuits, and relate these properties to quantified behaviours through modeling.
Key words: multisensory integration; sensory systems; motor systems; sensorimotor; balance; orientation & navigation; basal ganglia-thalamus-cortical loop; cerebellum; oculomotor systems; electrophysiological intrinsic properties and synaptic properties; microcirtuits; models of action selection; models of learning; statistical models; principle of maximum likelihood; baysian models; initial theories; memory &learning; Hebb theory and experimental demonstrations
Total number of hours: 24 Number of ECTS: 3 Semester 3
Optional course ☒
Prerequisites/skills needed: Master 1 in Neuroscience; basic knowledge regarding sensory and motor systems; basic knowledge about cellular electrophysiology
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Neurogenetics, psychiatry and behavior
Course supervisor:
- Nicolas RAMOZ (CR INSERM)
Description: This course aims to explain the interface between basic research in neuroscience, through different strategies, especially molecular biology of genetics, epigenetics and pharmacogenetics, and clinical research to understand behavior and psychiatric disorders. It also aims to present clinical research in order to show its contribution to the understanding of psychiatric diseases and the interest of developing translational research. In the end, this course aims to show by practical examples the interest of neuropsychiatric domains in the understanding of normal and pathological behaviors.
Key words: addiction, brain molecular biology, Epigenetics, Genetics, human behavior, psychopharmacogenetics, translational psychiatry
Total number of hours: 24 Number of ECTS: 3 Semester 3
Optional course ☒
Prerequisites/skills needed: M1 in science with a good understanding in fundamental neuroscience, genetics or molecular biology or M1 in health with the medical practice in neuroscience, psychiatry or pharmacology.
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: RNA regulation in the CNS
Course supervisor:
- Laure WEILL (MCU Université de Paris)
Description: The course provides an in-depth knowledge on RNA metabolism and RNA regulation and its role in neurobiology: brain development and cell differentiation, plasticity and how RNA deregulation can lead to different neuropathology.
Key words: Ribonucleopathy (splicing disease), RNA localization, local translation, non coding RNA, mRNA bodies
Total number of hours: 24 Number of ECTS: 3 Semester 3
Optional course ☒
Prerequisites/skills needed: Molecular Biology
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Brain Plasticity
Course supervisor:
- Isabelle CAILLE (MCU Université de Paris)
- Thierry GALLI (DR INSERM)
Description: Neural plasticity is the capacity of the nervous system to constantly modify itself throughout an individual’s life. The aim of this class will be to understand how behavioral experiences and neural activity can modify the structure and function of neural circuits. We will also consider how age and diseases can differentially affect these processes.
Key words: Structural plasticity, synaptic plasticity (LTP, LTD), Genomic Plasticity, synaptic pruning, autophagy, critical periods, learning and memory, adult neurogenesis, maladaptive plasticity in brain disorders and ageing, glial plasticity
Total number of hours: 24 Number of ECTS: 3 Semester 3
Optional course ☒
Prerequisites/skills needed: Knowledge in cellular and molecular neurobiology
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Nervous system disorders and repair
Course supervisor:
- Mehrnaz JAFARIAN-TEHRANI (Prof. Université de Paris)
Description: Recent advances in the pathophysiology of nervous system (CNS and PNS) disorders including neurodegenerative diseases, psychiatric disorders, movement disorders, pathologies of myelin, brain injury and cerebrovascular diseases, neurotropic viral infection, neuro-oncology and neuropathy. Some aspects of nervous system repair are taught related to stem cell therapy, neuroprotection, physical exercise and brain stimulation.
Key words: CNS and PNS disorders, Psychiatric disorders, Parkinson, Alzheimer, Huntington, Prion diseases, cerebrovascular diseases, stroke, brain injury, multiple sclerosis, movement disorders ALS, SMA, Neurotropic viral infections, Neuro-oncology
Total number of hours: 48 Number of ECTS: 3 Semester 3
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: Neurobiology, neuroanatomy
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Internship project and Research Internship
Course supervisor:
- Mehrnaz JAFARIAN-TEHRANI (Prof. Université de Paris),
- Isabelle CAILLE (MCU Université de Paris)
Description: An overall five to six-month internship is required to validate the M2 level. Before starting the internship, students have to present and defend their internship project (6 ECTS) at the beginning of semester 4. They have to contact their internship supervisor during semester 3 and spend time with the host research team in order to understand their research project.
Key words: Research teams, Europe, International, CNRS, INSERM, IPNP, Neurodiderot, Cochin, Necker, BFA, Institut Imagine, Campus Saint-Germain des Prés
Total number of hours: 5 to 6-month internship Number of ECTS: 6 ECTS (Internship project) + 24 ECTS (Research internship) Semester 4
Mandatory course ☒
Prerequisites/skills needed: Master Neuro S3
Teaching methods and activities: Experimental work, attending the neuroscience seminars
Exact Location: Research teams in France or abroad, but mainly research teams affiliated to the Paris University (see Master Neuro internship offers).
Assessment: written report and defense
Course Title: Research proposal
Course supervisor:
- Mehrnaz JAFARIAN-TEHRANI (Prof. Université de Paris),
- Isabelle CAILLE (MCU Université de Paris)
Description: To be able to write and defend a research proposal over 3 years based on a scientific publication, and fictive collaborations through interactions with the scientific community, researchers and engineers in research labs or technical facilities. The student has to write a proposal according to the instructions given at the beginning of the semester and finally be able to defend the proposal in front of a Jury.
Key words: Research project; experimental design; scientific report; scientific collaboration
Total number of hours: few practical sessions, mainly personal and team working Number of ECTS: 3 Semester 3
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: M1 Neuroscience (UE Methodologies in Neuroscience S1 and S2)
Teaching methods and activities: personal/team working (to be proactive and interactive with researchers/engineers)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: written report and defense
Course Title: Neural Data Science with Python
Course supervisor:
- Michael GRAUPNER (CR CNRS),
Description: Le domaine des neurosciences devient de plus en plus quantitatif et ce développement s’accompagne d’un torrent sans cesse croissant de données dérivées du cerveau. Il est essentiel que ce développement soit réalisé par les neuroscientifiques qui sont prêts et capables de traiter ces grosses données. La science des données est un domaine émergent qui se consacre à la compréhension des modèles dans les grands ensembles de données. Cette UEs vise à introduire la science des données neuronales – les principes de la science des données appliquées aux données neuronales.
Ce cours a pour but d’apprendre à analyser des données neurophysiologiques, de réaliser des modèles et des simulations de systèmes neuronaux en utilisant le language de programmation Python. Les étudiants seront initiés à l’utilisation de différentes bibliothèques de Pyhton générales et spécifiques telles que numpy, scipy, matplotlib, pandas, brian et à l’utilisation de l’environnement de Jupyter Noteook par navigateur.
Key words: Python, analyse des données, analyse des trains de spikes, modélisation biophysique, réseaux neuronaux, analyse spectrale, régression, réduction de la dimensionnalité, classification et regroupement, bioinformatique.
Total number of hours: 24 Number of ECTS: 3 Semester 1
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: Bases en neuroanatomie et physiologie du système nerveux central. Aucune connaissance préalable en programmation n’est requise car ce cours s’adresse aux débutants.
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Lab sessions
Course supervisor:
- Delphine MEFFRE (MCU Université de Paris),
- Damien CARREL (MCU Université de Paris),
Description: L’objectif de cet enseignement est de proposer aux étudiants 7 demi-journées de TP en neurosciences en s’appuyant sur les enseignements théoriques dispensés au premier semestre :
- neurosciences cognitives : électrophysiologie humaine
- sensorimotricité : TP plateforme
- neuropharmacologie: tests de comportement
- neurobiologie cellulaire : culture organotypique/cellulaire
- Imagerie : TP plateforme
- électrophysiologie sur tranche organotypique
- 1 TP Plateforme en petit groupe à choisir parmi une liste qui peut évoluer d’une année à l’autre : neurométabolisme ; oculomotricité ; mechanobiologie; cytométrie ; biochimie/crystallographie ; …
Cette formation comporte également une partie théorique sur les principes de techniques de pointe proposées par différentes plateformes, suivie d’un programme de visite.
Key words: neurosciences cognitives, sensorimotricité, neuropharmacologie, comportement, neurobiologie cellulaire, électrophysiologie, culture organotypique, imagerie, TP plateforme
Total number of hours: 28 Number of ECTS: 3 Semester 1
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: Biologie niveau Licence
Teaching methods and activities: Lab sessions (TP)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment
Course Title: Cellular mechanisms of neuropathologies
Course supervisor:
- Isabelle CAILLE (MCU Université de Paris),
- Damien CARREL (MCU Université de Paris)
- Thierry GALLI (DR INSERM)
Description: Comprendre les problématiques de biologie cellulaire spécifiques des cellules neuronales et leur dysfonctionnement dans différentes pathologies du système nerveux.
Key words: neuroscience cellulaire, neuroscience moléculaire, neurophatologies
Total number of hours: 24 Number of ECTS: 3 Semester 1
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: Biologie Cellulaire
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Du Neurone aux réseaux neuronaux
Course supervisor:
- Aude MARZO (MCU Université de Paris),
Description: L’UE « Du neurone au réseau neuronaux » a pour objectif de vous permettre de comprendre des enregistrements électrophysiologiques en partant sur des bases claires en électrophysiologie cellulaire. Il s’agit de comprendre les propriétés intrinsèques et extrinsèques des neurones et des synapses afin de pouvoir aborder leur communication au sein de réseaux.
Key words: Neurone, propriétés passives et actives, synapses
Total number of hours: 24 Number of ECTS: 3 Semester 1
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: Des connaissances solides en Biologie et Physiologie Cellulaire seront nécessaires
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Development and evolution of the nervous system
Course supervisor:
- Pierre KERNER (MCU Université de Paris),
Description: Comprendre l’origine embryonnaire et la connectivité des différents types cellulaires qui constituent le système nerveux central et périphérique des mammifères.
Retracer l’histoire évolutive du système nerveux par l’étude et la comparaison, chez différentes espèces, des caractères embryologiques et des processus qui gouvernent son développement.
Key words: Neuro-développement, évolution
Total number of hours: 24 Number of ECTS: 3 Semester 1
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: Avoir des connaissances de base du développement embryonnaire
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Sensorimotor and cognitive systems
Course supervisor:
- Olivier BIONDI (MCU Université de Paris),
- Laura DUGUE (MCU Université de Paris),
Description: MotorCog a pour objectif (1) de permettre aux étudiants de comprendre comment la motricité est finement régulée et contrôlée par le système sensoriel, via les récepteurs sensoriels spécialisés ou non; (2) de comprendre comment des fonctions cognitives supérieures peuvent émerger à partir de processus neurophysiologiques.
Dans la partie sensori-motrice, nous détaillerons le lien entre systèmes sensoriel et moteur et leur interrelation par des approches allant de la cellule aux fonctions cognitives complexes. Nous prendrons l’exemple du contrôle de la saccade oculaire et de la motricité volontaire afin de définir les régions cérébrales impliquées dans ces contrôles moteurs, leurs moyens d’intégration des informations multiples et la diversité des réponses possibles. Cela permettra de mieux comprendre la relation Homme/environnement et l’impact des situations sociales complexes (stress, peur, attention,….) dans le contrôle des mouvements.
Dans la partie cognitive, nous détaillerons la manière dont des principes basiques de neurophysiologie visuelle permettent d’étudier des fonctions cognitives supérieures telles la mémoire de travail, la prise de décision ou l’attention.
Key words: Récepteurs sensoriels, unités motrices, réseaux neuronaux, neuroanatomie, cognition
Total number of hours: 24 Number of ECTS: 3 Semester 1
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: Bases en neuroanatomie, physiologie du système nerveux central, physiologie du système musculaire squelettique et biologie cellulaire de niveau Bac+3
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Neuropharmacology
Course supervisor:
- Nicolas MARIE (CR CNRS),
- Mehrnaz JAFARIAN-TEHRANI (Prof. Université de Paris),
Description: La neuropharmacologie étudie l’effet d’un médicament ou d’une drogue sur le système nerveux. L’étudiant sera amené à acquérir les bases de la pharmacologie (pharmacométrie, pharmacocinétique, pharmacodynamie) avec une initiation à la neuropharmacologie moléculaire et comportementale.
Key words: Pharmacométrie, Pharmacocinétique, Pharmacodynamie, comportement, neuropharmacologie moléculaire
Total number of hours: 24 Number of ECTS: 3 Semester 1
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: Bases solides en physiologie.
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Neuroscience of homeostatic process
Course supervisor:
- Giuseppe GANGAROSSA (MCU Université de Paris)
Description: NeuroHome a l’objectif de donner aux étudiants une vision intégrative des processus homéostatiques (prise alimentaire et dépense énergétique, maintien température, régulation hydrique, rythme circadien, adaptation au stress, etc) et de leur control/régulation par le système nerveux. L’étudiant sera mené à considérer l’intégration des systèmes et des circuits neuronaux come la résultante des mécanismes homéostatiques et adaptatifs. Possibilité d’explorer les liens étroits entre fonctions cognitives (mémoire, apprentissage, motivation) et modifications homéostatiques centrales (glucose/lactate, respiration mitochondriale, adenosine).
Key words: Homéostasie, Neurosciences intégratives, Neurophysiologie des systèmes.
Total number of hours: 24 Number of ECTS: 3 Semester 1
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: Bases solides en physiologie, biologie cellulaire
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Functional neuroanatomy
Course supervisor:
- Clément RICARD (MCU Université de Paris)
Description: Donner aux étudiants du Master en Neurosciences une connaissance des bases de la neuroanatomie humaine d’un point de vue descriptif et fonctionnel qui leur sera utile dans la compréhension de toutes les autres UE du Master. Donner une vue d’ensemble des principales fonctions (somesthésie, vision, olfaction, goût, audition). Ouvrir ces connaissances anatomiques à la neuroanatomie des rongeurs, mettre en évidence les ressemblances et différences. Présenter les différentes méthodes d’imagerie utiles pour la réalisation d’études neuroanatomiques descriptives et/ou fonctionnelles.
Key words: Neuroanatomie descriptive, Neuroanatomie fonctionelle, Neuroimagerie.
Total number of hours: 24 Number of ECTS: 3 Semester 1
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: Aucun prérequis
Teaching methods and activities: Lectures (CM), Lab sessions (TP)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Models, experimental design and statistics
Course supervisor:
- Thérèse COLLINS (Prof. Université de Paris)
- Mehrnaz JAFARIAN-TEHRANI (Prof. Université de Paris)
Description: Ce module permettra à l’étudiant de compléter ses connaissances en méthodologies en continuité de l’UE proposée en S1. Cette UE couvre plusieurs aspects :
- Modèles animaux en neurosciences (rongeurs, animaux transgéniques, Zebrafish, Drosophile…)
- Modèles alternatifs : brain organoid, iPS
- Conception de protocoles expérimentaux en neurosciences
- Analyses statistiques appliquées en recherche expérimentale en neurosciences
- Bonnes pratiques en expérimentation animale
Key words: Modèles animaux (Animaux transgéniques, Zebrafish, rongeurs, Drosophile) ; Modèles alternatifs (brain organoid, iPS) ; Experimental design & Statistiques ; Bonnes pratiques en expérimentation animale
Total number of hours: 28 Number of ECTS: 3 Semester 2
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: Bases en sciences expérimentales et notions de statistiques ; UE communication scientifique S1 ; UE Travaux Pratiques S1
Teaching methods and activities: Lectures (CM), Practical sessions (TD)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Project management and scientific valorization
Course supervisor:
- Mathieu BERANECK (CR CNRS)
- Mehrnaz JAFARIAN-TEHRANI (Prof. Université de Paris)
Description: Ce module permettra à l’étudiant de compléter ses connaissances en méthodologies en continuité de l’UE proposée en S1.
Cette UE couvre plusieurs aspects :
- Ethique scientifique liée à l’expérimentation et à la communication scientifique (intégrité scientifique)
- Gestion de projet en recherche grâce aux outils utilisés en entreprise (voir PMI.org)
- Valorisation scientifique (Brevet, Start-up)
Key words: Gestion de projet ; Valorisation scientifique (Brevet, Start-up)
Total number of hours: 20 Number of ECTS: 3 Semester 2
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: UE communication scientifique S1
Teaching methods and activities: Lectures (CM), Practical sessions (TD), Lab sessions (TP)
Exact Location: Campus Saint-Germain des Prés, Faculty of Basic and Biomedical Sciences, 45 rue des Saints-Pères, 75006 Paris
Assessment: continuous assessment and exam
Course Title: Research Internship 1 and 2
Course supervisor:
- Mehrnaz JAFARIAN-TEHRANI (Prof. Université de Paris)
- Isabelle CAILLE (MCU Université de Paris)
- Damien CARREL (MCU Université de Paris)
Description: An overall four-month internship is required to validate the M1 level, either a long internship abroad, or 2 different internships of 2-month period. The idea of 2 internships is to cover different research projects in Neuroscience. We strongly recommend our students to go abroad at the first year M1. Our international relations office will help Master trainees before and during their mobility project. For the international incoming students, we recommend them to perform their internship in France.
Key words: Research teams, Europe, International, CNRS, INSERM, IPNP, Neurodiderot, Cochin, Necker, BFA, Institut Imagine, Campus Saint-Germain des Prés, UdP research facilities
Total number of hours: Two-month internship (x2) Number of ECTS: 12 (x2) Semester 2
Mandatory course ☒ Optional course ☐
Prerequisites/skills needed: Master Neuro S1
Teaching methods and activities: Experimental work, attending the neuroscience seminars
Exact Location: Research teams or research facilities affiliated to the Paris University (2 internships of 2-month period each, in different fields of neuroscience) or research teams abroad (1 internship of 4-month period) (cf. Master Neuro internship offers)
Assessment: Internship 1 (poster + defense); Internship 2 (report + defense)